Chiappini LabBioNano Engineering · KCL
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Research

Redefining how we interface with biology

The BioNano Engineering Lab, led by Dr Ciro Chiappini at King's College London, develops next-generation nanomaterials to interrogate and manipulate cells.

Our interdisciplinary team integrates nanotechnology, engineering biology and regenerative medicine to develop smart biomaterials that interact seamlessly with living systems. By engineering platforms for minimally invasive intracellular delivery and molecular sensing, we unlock new capabilities for spatiotemporal omics, in vivo gene therapy and personalised tissue regeneration.

Blue-tinted electron micrograph of a field of sharp nanoneedles.Nanomaterial DesignMaking porous silicon nanoneedles, nanowires and particles, and biodegradable devices for regenerative medicine.False-coloured electron micrograph of a gold cell spreading over blue nanoneedles.Biointerface EngineeringHow cells sense and respond when they touch a nanostructure, and how to design that contact.False-coloured electron micrograph of a pink cell sitting on green nanoneedles.Cell and Gene TherapyDelivering genes and gene editors into hard-to-transfect cells and tissues.Fluorescence image of tissue with a green-blue region bordering densely packed red-labelled cells.SpatioTemporal BiologySampling and sensing living tissue repeatedly to map how molecules change in space and time, and to diagnose disease without a biopsy.