People / Ciro Chiappini

Ciro Chiappini

Reader in BioNano Engineering · Associate Dean for Impact
Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London

Combining nanotechnology, bioengineering and cell biology to develop new approaches to advanced therapies and spatial biology.

£3M+ research funding
70+ publications
8,500+ citations
h-index 38
5 international patents

Citations and h-index: Google Scholar, October 2026

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Portrait of Ciro Chiappini, smiling, wearing glasses and a dark jumper over a white shirt.

About

Dr Ciro Chiappini is Reader in BioNano Engineering and Associate Dean for Impact at King’s College London. His research combines nanotechnology, bioengineering and cell biology to develop new approaches to advanced therapies and spatial biology.

His team is advancing nanoneedle technologies for gene delivery and editing in inherited skin and eye diseases, cell engineering, and repeated molecular sampling of living tissues. He also develops nanomaterials for regenerative medicine. His research has been supported by the ERC Starting Grant, UKRI, and the Chan Zuckerberg Initiative.

Before joining King’s, he held Newton International and Marie Skłodowska-Curie Fellowships at Imperial College London. He earned his PhD in Biomedical Engineering at the University of Texas at Austin. He has authored more than 70 publications and is an inventor on five patents.

Selected publications

Nanoneedles enable spatiotemporal lipidomics of living tissues

Gu C, Martella DA, Rose LA, Rouatbi N, Wang C, Zam A, Caprettini V, Jensen M, Liu S, Hagemann C, Memdouh S, …, Chiappini C

Nature Nanotechnology · 2025 · Open access version

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Mustfa SA, Dimitrievska M, Wang C, Gu C, Sun N, Romańczuk K, Karpinski P, Łaczmański Ł, McGrath JA, Jacków-Malinowska J, Chiappini C

Advanced Materials · 2025 · vol. 37, pp. e2414728

Tutorial: using nanoneedles for intracellular delivery

Chiappini C, Chen Y, Aslanoglou S, Mariano A, Mollo V, Mu H, De Rosa E, He G, Tasciotti E, Xie X, Santoro F, …, Elnathan R

Nature Protocols · 2021 · vol. 16, no. 10, pp. 4539–4563 · Open access version

Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization

Chiappini C, De Rosa E, Martinez JO, Liu X, Steele J, Stevens MM, Tasciotti E

Nature Materials · 2015 · vol. 14, no. 5, pp. 532–539 · Open access version

All publications

Contact

Centre for Craniofacial and Regenerative Biology, King's College London
27th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT
ciro.chiappini@kcl.ac.uk

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