The Chiappini Lab at King's College London engineers nanoneedles and nanomaterials to sample, sense and deliver into living cells and tissues.https://chiappinilab.com/https://chiappinilab.com/news/2026-10-13-phd-upgrades/https://chiappinilab.com/news/2026-10-13-phd-upgrades/Xinqi Zhong, Wellydo Escarião and Yuhan Lu have passed their MPhil-to-PhD upgrade, a key milestone in the King's doctoral programme.Tue, 13 Oct 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-07-08-crs-2026-lisbon-talk/https://chiappinilab.com/news/2026-07-08-crs-2026-lisbon-talk/Ciro presented Efficient nanoneedle transfection requires caveolar endocytosis in the Nanoscale Delivery IV session at the Controlled Release Society annual meeting.Wed, 08 Jul 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-05-21-chenlei-gu-tadion-rideal-prize/https://chiappinilab.com/news/2026-05-21-chenlei-gu-tadion-rideal-prize/Chenlei's PhD thesis, Engineering a Nanoneedle Biopsy Platform for Spatiotemporal Omics, has been awarded King's Tadion Rideal Prize.Thu, 21 May 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-05-18-biohub-spatiotemporal-omics-grant/https://chiappinilab.com/news/2026-05-18-biohub-spatiotemporal-omics-grant/Our project, Nanoneedle sampling of live tissue for spatiotemporal omics, is one of 15 teams funded by Biohub to watch inflammation unfold in living tissue.Mon, 18 May 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-05-15-nanocure-icure-explore/https://chiappinilab.com/news/2026-05-15-nanocure-icure-explore/After completing ICURe Discover, our nanoneedle-based local gene delivery project NanoCure, led by Yikai Wang, moves on to the ICURe Explore programme.Fri, 15 May 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-04-22-psst-2026-napoli/https://chiappinilab.com/news/2026-04-22-psst-2026-napoli/Yikai Wang, Hongting Zhu and Yusi Guo presented our nanostructured silicon platforms for EV manufacturing, restenosis and periodontal disease.Wed, 22 Apr 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-04-01-cartreg-microbioreactor-iscience/https://chiappinilab.com/news/2026-04-01-cartreg-microbioreactor-iscience/In iScience, we describe the KCL-Microbioreactor, a compact closed platform for small-batch manufacturing of CAR-Treg cell therapies.Wed, 01 Apr 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-03-30-nano-futures-roadmap/https://chiappinilab.com/news/2026-03-30-nano-futures-roadmap/We contributed the section on vertical nanoprobes to a new roadmap, Nano-enabled living materials and living electronics, in Nano Futures.Mon, 30 Mar 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-03-25-wcep-nanoelectroporation-session/https://chiappinilab.com/news/2026-03-25-wcep-nanoelectroporation-session/Ciro and Christelle Prinz (Lund University) co-chair a special session on nanoscale electroporation at the 6th World Congress on Electroporation, Daytona Beach, 27 Sept to 1 Oct 2026.Wed, 25 Mar 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-03-18-macrophage-optoporation-preprint/https://chiappinilab.com/news/2026-03-18-macrophage-optoporation-preprint/Led by Ines Poljak with Giulia Adriani's group, optoporation delivers genes to macrophages inside tumour spheroids to reshape immune phenotypes.Wed, 18 Mar 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-03-06-iit-madras-indo-uk-workshop/https://chiappinilab.com/news/2026-03-06-iit-madras-indo-uk-workshop/Ciro joined the Indo-UK Workshop on Nanomaterials in Biomedical Applications at IIT Madras, with colleagues from King's and the University of Leeds.Fri, 06 Mar 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-03-01-health-in-hyperdrive-podcast/https://chiappinilab.com/news/2026-03-01-health-in-hyperdrive-podcast/Ciro talked to Dominic James about nanoneedles, CRISPR delivery, nano-bandages for epidermolysis bullosa and biopsy-free sampling.Sun, 01 Mar 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-02-23-cure-eb-nanocure-video/https://chiappinilab.com/news/2026-02-23-cure-eb-nanocure-video/Cure EB has released a video of Ciro describing NanoCure, the charity-funded project developing nanoneedle bandages to deliver collagen VII gene therapy.Mon, 23 Feb 2026 00:00:00 GMThttps://chiappinilab.com/news/2026-02-06-caveolar-endocytosis-acs-nano/https://chiappinilab.com/news/2026-02-06-caveolar-endocytosis-acs-nano/In ACS Nano, we show that Caveolin-1-dependent caveolar endocytosis is what turns nanoneedle delivery into gene expression.Fri, 06 Feb 2026 00:00:00 GMThttps://chiappinilab.com/news/2025-12-16-eb4bm-launch/https://chiappinilab.com/news/2025-12-16-eb4bm-launch/King's, Leeds and NPL launch Engineering Biology for Biomedicine, a BBSRC Doctoral Focal Award training around 40 PhD researchers. The lab is part of the programme.Tue, 16 Dec 2025 00:00:00 GMThttps://chiappinilab.com/news/2025-12-01-ctm-commentary-spatiotemporal-omics/https://chiappinilab.com/news/2025-12-01-ctm-commentary-spatiotemporal-omics/In Clinical and Translational Medicine, Ciro explains how spatiotemporal omics in living tissue could change tumour profiling.Mon, 01 Dec 2025 00:00:00 GMThttps://chiappinilab.com/news/2025-11-13-mdpi-nanomaterials-webinar/https://chiappinilab.com/news/2025-11-13-mdpi-nanomaterials-webinar/Ciro spoke alongside Frédérique Cunin (CNRS) at the Nanomaterials (MDPI) webinar on nanoscale platforms for drug delivery.Thu, 13 Nov 2025 00:00:00 GMThttps://chiappinilab.com/news/2025-06-16-spatiotemporal-lipidomics-nature-nanotechnology/https://chiappinilab.com/news/2025-06-16-spatiotemporal-lipidomics-nature-nanotechnology/In Nature Nanotechnology, nanoneedles repeatedly sample live brain tissue for spatial lipidomics, without destroying it.Mon, 16 Jun 2025 00:00:00 GMThttps://chiappinilab.com/news/2025-04-15-car-treg-nanoneedle-electroporation/https://chiappinilab.com/news/2025-04-15-car-treg-nanoneedle-electroporation/In Advanced Science, a scalable nanoneedle electroporation platform transfects primary human Tregs with CAR plasmids, a non-viral route to CAR-Treg production.Tue, 15 Apr 2025 00:00:00 GMThttps://chiappinilab.com/news/2025-03-12-base-editing-rdeb-advanced-materials/https://chiappinilab.com/news/2025-03-12-base-editing-rdeb-advanced-materials/In Advanced Materials, nanoneedle delivery of an adenine base editor corrects a COL7A1 variant in patient cells with recessive dystrophic epidermolysis bullosa.Wed, 12 Mar 2025 00:00:00 GMThttps://chiappinilab.com/news/2024-10-17-organoid-optoporation-advanced-materials/https://chiappinilab.com/news/2024-10-17-organoid-optoporation-advanced-materials/In Advanced Materials, porous silicon nanoparticles and laser pulses deliver nucleic acids into chosen regions of 3D organoid cultures.Thu, 17 Oct 2024 00:00:00 GMT